Publications

Financially Adaptive Clinical Trials via Option Pricing Analysis

2020
Chaudhuri, Shomesh E. and Andrew W. Lo (2020),Financially adaptive clinical trials via option pricing analysis, Journal of Econometrics , 1-11.

Estimating the Financial Impact of Gene Therapy

2020
Wong, Chi Heem, Dexin Li, Nina Wang, Jonathan Gruber, Rena Conti, and Andrew W. Lo (2020), Estimating the Financial Impact of Gene Therapy (Preprint), medRxiv 2020.10.27.20220871, https://doi.org/10.1101/2020.10.27.20220871.

A Brain Capital Grand Strategy: Toward Economic Reimagination

2020
Smith, Erin, Diab Ali, Bill Wilkerson, Walter D. Dawson, Kunmi Sobowale, Charles Reynolds III, Michael Berk, Helen Lavretsky, Dilip Jeste, Chee Ng, Jair C. Soares, Gowri Aragam, Zoe Wainer, Husseini K. Manji, Julio Licinio, Andrew W. Lo, Eric Storch, Ernestine Fu, Marion Leboyer, Ioannis Tarnanas, Agustin Ibanez, Facundo Manes, Sarah Caddick, Howard Fillit, Ryan Abbott, Ian H. Robertson, Sandra B. Chapman, Rhoda Au, Cara M. Altimus, William Hynes, Patrick Brannelly, Jeffrey Cummings, and Harris A. Eyre (2020), A Brain Capital Grand Strategy: Toward Economic Reimagination, Molecular Psychiatry, https://doi.org/10.1038/s41380-020-00918-w.

A Cost/Benefit Analysis of Clinical Trial Designs for COVID-19 Vaccine Candidates

2020
Berry, Donald, Scott Berry, Peter Hale, Leah Isakov, Andrew W. Lo, Kien Wei Siah, and Chi Heem Wong (2020), A Cost/Benefit Analysis of Clinical Trial Designs for COVID-19 Vaccine Candidates (Preprint), medRxiv 2020.09.15.20195495, https://doi.org/10.1101/2020.09.15.20195495.

Financing Correlated Drug Development Projects

2020
Lo, Andrew W., and Kien Wei Siah (2020), Financing Correlated Drug Development Projects, Journal of Structured Finance, forthcoming .

The Challenging Economics of Vaccine Development in the Age of COVID-19, and What Can Be Done About It

2020
Vu, Jonathan, Ben Kaplan, Shomesh E. Chaudhuri, Monique Mansoura, and Andrew W. Lo (2020), The Challenging Economics of Vaccine Development in the Age of COVID-19, and What Can Be Done About It, DIA Global Forum 12 (5).

Financing Vaccines for Global Health Security

2020
Vu, Jonathan, Ben Kaplan, Shomesh E. Chaudhuri, Monique Mansoura, and Andrew W. Lo (2020), "Financing Vaccines for Global Health Security."

Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks

2020
Chaudhuri, Shomesh, Andrew W. Lo, Xiao, Danyang, and Xu, Qingyang (2020), Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks, Harvard Data Science Review.

Estimating Probabilities of Success of Vaccine and Other Anti-Infective Therapeutic Development Programs

2020
Lo, Andrew W., Kien Wei Siah, and Chi Heem Wong (2020), Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti‐Infective Therapeutics, Harvard Data Science Review.

Fair and Responsible Drug Pricing: A Case Study of Radius Health and Abaloparatide

2020
Xu, Qingyang, and Andrew W. Lo (2020), Fair and Responsible Drug Pricing: A Case Study of Radius Health and abaloparatide, Journal of Investment Management 18 (1), 90-98.

Venture Philanthropy: A Case Study of the Cystic Fibrosis Foundation

2019
Kim, Esther, and Andrew W. Lo (2019), Venture Philanthropy: A Case Study of the Cystic Fibrosis Foundation, April 23.

Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non–Small-Cell Lung Cancer

2019
Siah, Kien Wei, Sean Khozin, Chi Heem Wong, and Andrew W. Lo (2019), Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non–Small-Cell Lung Cancer, JCO Clinical Cancer Informatics 3, 1–11.

Funding Long Shots

2019
Hull, John, Andrew W. Lo, and Roger M. Stein (2019), Funding Long Shots, Journal of Investment Management 17 (4), 1–33.

Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations

2019
Angus, Derek C., Brian M. Alexander, Scott Berry, et. al. (2019), Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations, Nature Reviews Drug Discovery 18 (10), 797–807.

What Are the Chances of Getting a Cancer Drug Approved?

2019
Wong, Chi Heem, Kien Wei Siah, and Andrew W. Lo (2019), What Are the Chances of Getting a Cancer Drug Approved?, DIA Global Forum, May.