Publications

How to pay for individualized genetic medicines

2024
Pian, Julia M. Y., Nana Owusu, Julia Vitarello, Winston X. Yan, Andrew W. Lo and Timothy W. Yu (2024), How to pay for individualized genetic medicines, Nature Medicine.

How does news affect biopharma stock prices?: An event study

2024
Cho, Joonhyuk, Manish Singh, and Andrew W. Lo (2024), How Does News Affect Biopharma Stock Prices?: An Event Study, PLoS One 19 (1), e0296927.

Financially Adaptive Clinical Trials via Option Pricing Analysis

2024
Chaudhuri, Shomesh E., and Andrew W. Lo (2024),Financially adaptive clinical trials via option pricing analysis, Journal of Econometrics 240 (2), 105026. https://doi.org/10.1016/j.jeconom.2020.08.012.

A Review of Economic Issues for Gene-Targeted Therapies: Value, Affordability, and Access

2023
Garrison, Louis P., Andrew W. Lo, Richard S. Finkel, and Patricia A. Deverka (2023), A Review of Economic Issues for Gene-Targeted Therapies: Value, Affordability, and Access, American Journal of Medical Genetics Part C: Seminars in Medical Genetics 193 (1), 64–76.

Financing Repurposed Drugs for Rare Diseases: A Case Study of Unravel Biosciences

2023
Bechara, Abouarab, Christian Bazarian, Zied Ben Chaouch, Andrew W. Lo, Guillermo Mourenza Gonzalez, Richard Novak, and Frederic Vigneault (2023), Financing Repurposed Drugs for Rare Diseases: A Case Study of Unravel Biosciences, Orphanet Journal of Rare Diseases 18, 287. https://doi.org/10.1186/s13023-023-02753-y.

Use of Bayesian Decision Analysis to Maximize Value in Patient-Centered Randomized Clinical Trials in Parkinson’s Disease

2023
Chaudhuri, Shomesh E., Zied Ben Chaouch, Brett Hauber, Brennan Mange, Mo Zhou, Stephanie Christopher, Dawn Bardot, Margaret Sheehan, Anne Donnelly, Lauren McLaughlin, Brittany Caldwell, Heather L. Benz, Martin Ho, Anindita Saha, Katrina Gwinn, Murray Sheldon, and Andrew W. Lo (2023), Use of Bayesian Decision Analysis to Maximize Value in Patient-Centered Randomized Clinical Trials in Parkinson’s Disease, Journal of Biopharmaceutical Statistics, https://doi.org/10.1080/10543406.2023.2170400.

Patient-Centered Clinical Trial Design for Heart Failure Devices via Bayesian Decision Analysis

2023
Chaudhuri, Shomesh E., Phillip Adamson, Dean Bruhn-Ding, Zied Ben Chaouch, David Gebben, Lilian Rincon-Gonzalez, Barry Liden, Shelby D. Reed, Anindita Saha, Daniel Schaber, Kenneth Stein, Michelle E. Tarver, and Andrew W. Lo (2023), Patient-Centered Clinical Trial Design for Heart Failure Devices via Bayesian Decision Analysis, The Patient: Patient-Centered Outcomes Research 16 (4), 359–369.

Accelerating Vaccine Innovation for Emerging Infectious Diseases via Parallel Discovery

2023
Barberio, Joseph, Jacob Becraft, Zied Ben Chaouch, Dimitris Bertsimas, Tasuku Kitada, Michael L. Li, Andrew W. Lo, Kevin Shi, and Qingyang Xu (2023), Accelerating Vaccine Innovation for Emerging Infectious Diseases via Parallel Discovery, Entrepreneurship and Innovation Policy and the Economy 2, 9–39.

The Estimated Annual Financial Impact of Gene Therapy in the United States

2023
Wong, Chi Heem, Dexin Li, Nina Wang, Jonathan Gruber, Andrew W. Lo, and Rena M. Conti (2023), The Estimated Annual Financial Impact of Gene Therapy in the United States 30, 761–773.

Leveraging Patient Preference Information in Medical Device Clinical Trial Design

2023
Rincon-Gonzalez, Lilianna, Wendy K. D. Selig, Brett Hauber, Shelby D. Reed, Michelle E. Tarver, Shomesh E. Chaudhuri, Andrew W. Lo, Dean Bruhn-Ding, and Barry Liden (2023), Leveraging Patient Preference Information in Medical Device Clinical Trial Design, Therapeutic Innovation & Regulatory Science 57, 152–159.

Financial Intermediation and the Funding of Biomedical Innovation: A Review

2023
Lo, Andrew W., and Richard T. Thakor (2023), Financial Intermediation and the Funding of Biomedical Innovation: A Review, Journal of Financial Intermediation 54, 101028, https://doi.org/10.1016/j.jfi.2023.101028.

Pandemic Readiness Requires Bold Federal Financing for Vaccines

2022
Lo, Andrew W., and Ishan Sharma (2022), Pandemic Readiness Requires Bold Federal Financing for Vaccines, Federation of American Scientists, October 25.

Financing pharmaceuticals and medical devices for pain treatment and opioid use disorder

2022
Siah, Kien-Wei, Dermot P. Maher, and Andrew W. Lo (2022), Financing pharmaceuticals and medical devices for pain treatment and opioid use disorder, Emerging Trends in Drugs, Addictions, and Health 2, 100045.

Identifying and Mitigating Potential Biases in Predicting Drug Approvals

2022
Xu, Qingyang, Elaheh Ahmadi, Alexander Amini, Daniela Rus, and Andrew W. Lo, Identifying and Mitigating Potential Biases in Predicting Drug Approvals, Drug Safety 45, 521–533.

Incorporating patient preferences and burden-of-disease in evaluating ALS drug candidate AMX0035: a Bayesian decision analysis perspective

2022
Xu, Qingyang, Joonhyuk Cho, Zied Ben Chaouch, and Andrew W. Lo (2022), Incorporating patient preferences and burden-of-disease in evaluating ALS drug candidate AMX0035: a Bayesian decision analysis perspective, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24 (3–4), 281–288.