Publications

Predicting drug approvals: The Novartis data science and artificial intelligence challenge

2021
Wei Siah, Kien, Nicholas W. Kelley, Steffen Ballerstedt, Bjorn Holzhauer, Tianmeng Lyu, David Mettler, Sophie Sun, Simon Wandel, Yang Zhong, Bin Zhou, Shifeng Pan, Yingyao Zhou, and Andrew W. Lo (2021), Predicting drug approvals: The Novartis data science and artificial intelligence challenge, Patterns 2 (8), 1-9.

Can Financial Economics Cure Cancer?

2021
Lo, Andrew W. (2021), Can Financial Economics Cure Cancer?, Atlantic Economic Journal 49, 3–21.

Parkinson’s Patients’ Tolerance for Risk and Willingness to Wait for Potential Benefits of Novel Neurostimulation Devices: A Patient-Centered Threshold Technique Study

2021
Hauber, Brett, Brennan Mange, Mo Zhou, Shomesh Chaudhuri, Heather L. Benz, Brittany Caldwell, John P. Ruiz, Anindita Saha, Martin Ho, Stephanie Christopher, Dawn Bardot, Margaret Sheehan, Anne Donnelly, Lauren McLaughlin, Katrina Gwinn, Andrew Lo, and Murray Sheldon (2021), Parkinson's Patients' Tolerance for Risk and Willingness to Wait for Potential Benefits of Novel Neurostimulation Devices: A Patient-Centered Threshold Technique Study, MDM Policy & Practice 6 (1), https://doi.org/10.1177/2381468320978407.

Accelerating glioblastoma therapeutics via venture philanthropy

2021
Siah, Kien Wei, Qingyang Xu, Kirk Tanner, Olga Futer, John J. Frishkopf, and Andrew W. Lo (2021), Accelerating glioblastoma therapeutics via venture philanthropy, Drug Discovery Today 26 (7), 1744-1749. https://doi.org/10.1016/j.drudis.2021.03.020.

Incorporating Patient Preferences via Bayesian Decision Analysis

2021
Chaudhuri, Shomesh E., and Andrew W. Lo (2021), Incorporating Patient Preferences via Bayesian Decision Analysis, Clinical Journal of the American Society of Nephrology 16 (1), 639–641.

Life sciences intellectual property licensing at the Massachusetts Institute of Technology

2021
Huang, Samuel, Kien Wei Siah, Detelina Vasileva, Shirley Chen, Lita Nelsen & Andrew W. Lo (2021), Life sciences intellectual property licensing at the Massachusetts Institute of Technology, Nature Biotechnology 39, 293–301 .

A Brain Capital Grand Strategy: Toward Economic Reimagination

2021
Smith, Erin, Diab Ali, Bill Wilkerson, Walter D. Dawson, Kunmi Sobowale, Charles Reynolds III, Michael Berk, Helen Lavretsky, Dilip Jeste, Chee Ng, Jair C. Soares, Gowri Aragam, Zoe Wainer, Husseini K. Manji, Julio Licinio, Andrew W. Lo, Eric Storch, Ernestine Fu, Marion Leboyer, Ioannis Tarnanas, Agustin Ibanez, Facundo Manes, Sarah Caddick, Howard Fillit, Ryan Abbott, Ian H. Robertson, Sandra B. Chapman, Rhoda Au, Cara M. Altimus, William Hynes, Patrick Brannelly, Jeffrey Cummings, and Harris A. Eyre (2021), A Brain Capital Grand Strategy: Toward Economic Reimagination, Molecular Psychiatry 26, 3–22.

Financing Correlated Drug Development Projects

2021
Lo, Andrew W., and Kien Wei Siah (2021), Financing Correlated Drug Development Projects, Journal of Structured Finance 27 (1), 17–34, https://doi.org/10.3905/jsf.2020.1.114 .

A Cost/Benefit Analysis of Clinical Trial Designs for COVID-19 Vaccine Candidates

2020
Berry, Donald, Scott Berry, Peter Hale, Leah Isakov, Andrew W. Lo, Kien Wei Siah, Chi Heem Wong (2020), A Cost/Benefit Analysis of Clinical Trial Designs for COVID-19 Vaccine Candidates, PLoS ONE 15(12): e0244418.

The Challenging Economics of Vaccine Development in the Age of COVID-19, and What Can Be Done About It

2020
Vu, Jonathan, Ben Kaplan, Shomesh E. Chaudhuri, Monique Mansoura, and Andrew W. Lo (2020), The Challenging Economics of Vaccine Development in the Age of COVID-19, and What Can Be Done About It, DIA Global Forum 12 (5).

Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks

2020
Chaudhuri, Shomesh, Andrew W. Lo, Xiao, Danyang, and Xu, Qingyang (2020), Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks, Harvard Data Science Review, https://doi.org/10.1162/99608f92.7656c213.

Fair and Responsible Drug Pricing: A Case Study of Radius Health and Abaloparatide

2020
Xu, Qingyang, and Andrew W. Lo (2020), Fair and Responsible Drug Pricing: A Case Study of Radius Health and abaloparatide, Journal of Investment Management 18 (1), 90-98.

Estimating Probabilities of Success of Vaccine and Other Anti-Infective Therapeutic Development Programs

2020
Lo, Andrew W., Kien Wei Siah, and Chi Heem Wong (2020), Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti‐Infective Therapeutics, Harvard Data Science Review.

Venture Philanthropy: A Case Study of the Cystic Fibrosis Foundation

2019
Kim, Esther, and Andrew W. Lo (2019), Venture Philanthropy: A Case Study of the Cystic Fibrosis Foundation, April 23.

Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations

2019
The Adaptive Platform Trials Coalition (2019), Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations, Nature Reviews Drug Discovery 18 (10), 797–807.