Publications

Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non–Small-Cell Lung Cancer

2019
Siah, Kien Wei, Sean Khozin, Chi Heem Wong, and Andrew W. Lo (2019), Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non–Small-Cell Lung Cancer, JCO Clinical Cancer Informatics 3, 1–11.

What Are the Chances of Getting a Cancer Drug Approved?

2019
Wong, Chi Heem, Kien Wei Siah, and Andrew W. Lo (2019), What Are the Chances of Getting a Cancer Drug Approved?, DIA Global Forum, May.

Bridging the Valley of Death Through Financial Innovation

2019
Lo, Andrew W. (2019), Congressional Testimony: Bridging the Valley of Death Through Financial Innovation, September 11.

Risk and Reward in the Orphan Drug Industry

2019
Lo, Andrew W., and Richard T. Thakor (2019), Risk and Reward in the Orphan Drug Industry, Journal of Portfolio Management 45 (5), 30–45.

Machine Learning with Statistical Imputation for Predicting Drug Approvals

2019
Lo, Andrew W., Kien Wei Siah, and Chi Heem Wong (2019), Machine Learning with Statistical Imputation for Predicting Drug Approval, Harvard Data Science Review 1 (1).

A Portfolio Approach to Accelerate Therapeutic Innovation in Ovarian Cancer

2019
Chaudhuri, Shomesh E., Katherine Cheng, Andrew W. Lo, Shirley Pepke, Sergio Rinaudo, Lynda Roman, and Ryan Spencer (2019), A Portfolio Approach to Accelerate Therapeutic Innovation in Ovarian Cancer, Journal of Investment Management 17 (2), 5–16.

Acceleration of Rare Disease Therapeutic Development: A Case Study of AGIL-AADC

2019
Das, Sonya, Samuel Huang, and Andrew W. Lo (2019), Acceleration of Rare Disease Therapeutic Development: A Case Study of AGIL-AADC, Drug Discovery Today 24 (3), 678–684.

Estimation of Clinical Trial Success Rates and Related Parameters

2019
Wong, Chi Heem, Kien Wei Siah, and Andrew W. Lo (2019), Estimation of Clinical Trial Success Rates and Related Parameters, Biostatistics 20 (2), 273–286. https://doi.org/10.1093/biostatistics/kxx069.

Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design

2019
Isakov, Leah, Andrew W. Lo, and Vahid Montazerhodjat (2019), Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design, Journal of Econometrics 211 (1), 117–136.

Alzheimer’s Disease is About to Become a Crisis. Here’s How California Could Lead

2018
Kosik, Kenneth S., and Andrew W. Lo (2018), Alzheimer’s Disease is About to Become a Crisis. Here’s how California Could Lead, Sacramento Bee, May 22.

Doing Well By Doing Good

2018
Lo, Andrew W. (2018), Doing Well by Doing Good, RISK, December 12.

New Business Models to Accelerate Innovation in Pediatric Oncology Therapeutics: A Review

2018
Das, Sonya, Raphaël Rousseau, Peter C. Adamson, and Andrew W. Lo (2018), New Business Models to Accelerate Innovation in Pediatric Oncology Therapeutics: A Review, JAMA Oncology 4 (9), 1274–1280.

Patient-Centered Clinical Trials

2018
Chaudhuri, Shomesh E., Martin P. Ho, Telba Irony, Murray Sheldon, and Andrew W. Lo (2018), Patient-Centered Clinical Trials, Drug Discovery Today 23 (2), 395–401.

Use of Bayesian Decision Analysis to Minimize Harm in Patient-Centered Randomized Clinical Trials in Oncology

2017
Montazerhodjat, Vahid, Shomesh E. Chaudhuri, Daniel J. Sargent, and Andrew W. Lo (2017), Use of Bayesian Decision Analysis to Minimize Harm in Patient-Centered Randomized Clinical Trials in Oncology, JAMA Oncology 3 (9), e170123.

Pricing for Survival in the Biopharma Industry: A Case Study of Acthar Gel and Questcor Pharmaceuticals

2017
Burnham, Terence C., Samuel Huang, and Andrew W. Lo (2017), Pricing for Survival in the Biopharma Industry: A Case Study of Acthar Gel and Questcor Pharmaceuticals, Journal of Investment Management 15 (4), 69–91.