Publications

Risk and Reward in the Orphan Drug Industry

2019
Lo, Andrew W., and Richard T. Thakor (2019), Risk and Reward in the Orphan Drug Industry, Journal of Portfolio Management 45 (5), 30–45.

Machine Learning with Statistical Imputation for Predicting Drug Approvals

2019
Lo, Andrew W., Kien Wei Siah, and Chi Heem Wong (2019), Machine Learning with Statistical Imputation for Predicting Drug Approval, Harvard Data Science Review 1 (1).

A Portfolio Approach to Accelerate Therapeutic Innovation in Ovarian Cancer

2019
Chaudhuri, Shomesh E., Katherine Cheng, Andrew W. Lo, Shirley Pepke, Sergio Rinaudo, Lynda Roman, and Ryan Spencer (2019), A Portfolio Approach to Accelerate Therapeutic Innovation in Ovarian Cancer, Journal of Investment Management 17 (2), 5–16.

Annals Issue in Honor of Jerry A. Hausman

2019
Aït-Sahalia, Yacine, Andrew W. Lo, and Whitney K. Newey (2019), Annals Issue in Honor of Jerry Hausman: Editors’ Introduction, Journal of Econometrics 211 (1), 1–3.

Acceleration of Rare Disease Therapeutic Development: A Case Study of AGIL-AADC

2019
Das, Sonya, Samuel Huang, and Andrew W. Lo (2019), Acceleration of Rare Disease Therapeutic Development: A Case Study of AGIL-AADC, Drug Discovery Today 24 (3), 678–684.

Dynamic Alpha: A Spectral Decomposition of Investment Performance Across Time Horizons

2019
Chaudhuri, Shomesh E., and Andrew W. Lo (2019), Dynamic Alpha: A Spectral Decomposition of Investment Performance Across Time Horizons, Management Science 65 (9), 4440–4450.

Estimation of Clinical Trial Success Rates and Related Parameters

2019
Wong, Chi Heem, Kien Wei Siah, and Andrew W. Lo (2019), Estimation of Clinical Trial Success Rates and Related Parameters, Biostatistics 20 (2), 273–286. https://doi.org/10.1093/biostatistics/kxx069.

Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design

2019
Isakov, Leah, Andrew W. Lo, and Vahid Montazerhodjat (2019), Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design, Journal of Econometrics 211 (1), 117–136.

On Black’s Leverage Effect in Firms with No Leverage

2019
Hasanhodzic, Jasmina, and Andrew W. Lo (2019), On Black’s Leverage Effect in Firms with No Leverage, Journal of Portfolio Management 46 (1), 106–122.

What Do Humans Perceive in Asset Returns?

2019
Hasanhodzic, Jasmina, Andrew W. Lo, and Emanuele Viola (2019), What Do Humans Perceive in Asset Returns?, Journal of Portfolio Management 45 (4), 49–60.
Jasmina Hasanhodzic and Emanuele Viola

Alzheimer’s Disease is About to Become a Crisis. Here’s How California Could Lead

2018
Kosik, Kenneth S., and Andrew W. Lo (2018), Alzheimer’s Disease is About to Become a Crisis. Here’s how California Could Lead, Sacramento Bee, May 22.

Biological Economics

2018
Lo, Andrew W., and Ruixun Zhang (2018), Biological Economics, edited volume, Edward Elgar Publishing.

The Visible Hand: A Review of The Guidance of an Enterprise Economy

2018
Lo, Andrew W. (2018), The Visible Hand: A Review of The Guidance of an Enterprise Economy by Martin Shubik and Eric Smith, Accounting, Economics, and Law: A Convivium 9 (3), 592.

If Liberal Democracies Can Resist the Urge to Micromanage the Economy, Big Data Could Catalyze a New Capitalism

2018
Lo, Andrew W. (2018), If Liberal Democracies Can Resist the Urge to Micromanage the Economy, Big Data Could Catalyze a New Capitalism, Science 359 (6376), 644.

If Regulations Don’t Bend, They’ll Break

2018
Lo, Andrew W. (2018), If Regulations Don’t Bend, They’ll Break, RISK, July 2.